Skip to content

Topic hub

Cross-Disciplinary Deep Essays

Where biology, computation, markets, and philosophy collide.

The flagship long-form: rigorous essays that borrow from one field to see another more clearly — evolution and strategy, computation and cognition, the philosophy of science and the practice of building. The pieces that only this platform would publish.

33 essays

Slow Takeoff Is the Default — and Slow Is Not Safe

The takeoff debate is staged as fast singleton versus slow diffusion. Slow is both more likely and already underway — which doesn't remove the danger, it relocates it to concentration, disruption, and gradual loss of oversight.

10 min read

The One MAMMAL Result That Ran in a Wet Lab

MAMMAL posts state-of-the-art on nine benchmarks, but the result that matters is four potency predictions on drugs it never saw, confirmed by a real assay. Here's why that one experiment outweighs the leaderboard.

8 min read

Every Business Is an Arbitrage With a Closing Window

Every way of making money is an arbitrage — a bet on a price difference the market hasn't closed. That reframes strategy as two questions: what exactly is your mispricing, and how long until the window shuts.

8 min read

Why Most AI Strategy Is Biologically Illiterate

Companies deploy AI like installing software. The right model is introducing an organism into an ecosystem, and selection pressure predicts the failure modes the ROI math can't see.

10 min read

Scaling Is Not a Theory of Intelligence

The scaling hypothesis is the most successful empirical regularity in the history of machine learning and an explanation of nothing. The industry has bet its capital structure on a line it cannot explain continuing straight.

9 min read

The Automated Scientist Is a Category Error

Science is not hypothesis generation, which is cheap and always was. It is the disciplined killing of hypotheses against reality, plus the taste to pick which are worth testing — and neither is a text problem.

10 min read

Trusting an AI Is the 250-Year-Old Problem of Believing a Stranger

"Should I trust what the AI told me" is the epistemology of testimony applied to a testifier with unknown reliability, no stable identity, and no accountability — exactly the configuration where philosophers say default trust is unwarranted.

9 min read

Regression to the Mean Is Eating Your Growth Numbers

Most growth spikes companies celebrate and slumps they panic over are regression to the mean — statistical gravity, not signal. Mistaking it for causation rewards noise and punishes sense.

8 min read

Go deeper on essays.

Get new Cross-Disciplinary Deep Essays essays — and the best of the other six pillars — delivered as they publish.

Thoughtful essays. No spam. Unsubscribe anytime.

Explore other topics